| Introduction | aminocaproic acid (also known as 6-aminocaproic acid) is an antifibrinolytic agent. Fibrinogen specifically binds to fibrin through the lysine binding site in its molecular structure, and then becomes plasmin under the action of activator, which can cleave arginine and lysine peptide chains in fibrin, fibrin degradation products are formed to dissolve the blood clot. Aminocaproic acid can qualitatively inhibit the binding of plasminogen to fibrin and prevent its activation, thereby inhibiting fibrinolysis. High concentration (100mg/L) directly inhibits the activity of plasmin and achieves the hemostatic effect. |
| indication | aminocaproic acid is suitable for the prevention and treatment of various bleeding caused by hyperfibrinolysis. |
| pharmacological action | aminocaproic acid is an antifibrinolytic agent. Fibrinogen specifically binds to fibrin through the lysine binding site in its molecular structure, and then becomes plasmin under the action of activator, which can cleave arginine and lysine peptide chains in fibrin, fibrin degradation products are formed to dissolve the blood clot. The chemical structure of this product is similar to lysine, which can qualitatively inhibit the combination of plasminogen and fibrin, prevent its activation, and inhibit fibrinolysis. High concentration (100mg/L) directly inhibits the activity of fibrinolytic enzyme, hemostasis was achieved. |
